Community Outreach - Routine Immunization Increased: 54% mean proportion
Arm B - additional interventions with community outreach and mobilisation; Arm C all interventions of arm B with additional provision of inactivated polio vaccine (IPV) delivered at the maternal and child health camps
54% mean proportion of routine vaccine doses received in Arm C (43% in Arm A & 52% in Arm B).
Country of study
Conflict-affected areas of Pakistan
Cluster RCT - 387 clusters, 28,760 children
Journal paper title and link
Community engagement and integrated health and polio immunisation campaigns in conflict-affected areas of Pakistan: a cluster randomised controlled trial
Excerpt from Abstract
"Between June 4, 2013, and May 31, 2014, 387 clusters were randomised (131 to arm A, 127 to arm B, and 129 to arm C). At baseline, 28 760 children younger than 5 years were recorded in arm A, 30 098 in arm B, and 29 126 in arm C. 359 clusters remained in the trial until the end (116 in arm A, 120 in arm B, and 123 in arm C; with 23 334 children younger than 5 years in arm A, 26 110 in arm B, and 25 745 in arm C). The estimated OPV coverage was 75% in arm A compared with 82% in arm B (difference vs arm A 6·6%; 95% CI 4·8–8·3) and 84% in arm C (8·5%, 6·8–10·1; overall p<0·0001). The mean proportion of routine vaccine doses received by children younger than 24 months of age was 43% in arm A, 52% in arm B (9%, 7–11) and 54% in arm C (11%, 9–13; overall p<0·0001). No serious adverse events requiring hospitalisation were reported after immunisation."